Metabolic Health

Glyciphage SR Tablet

Reviewed by

Shifa Fathima

Glyciphage SR

Glyciphage SR 500mg Tablet is prescribed by medical practitioners to people with diabetes. It is given to people with type 2 diabetes which is also known as adult-onset diabetes. In the simplest terms, it is prescribed when the body is not sensitive to insulin or it is not producing the required amount. It is a prolonged condition and mostly irreversible. 

Given the type of diabetes, the first option is to try and control the blood sugar levels by exercising and committing to a particular type of diet. When that alone is not helping, this is the first line of defense for the body. 

What is Glyciphage?

Glyciphage is a drug prescribed to those with diabetes that belongs to the biguanide class of medicines. It consists of Metformin hydrochloride and lowers glucose production in the liver. At the same time, it delays the absorption of glucose from the intestines to maintain blood sugar levels. 

Uses of Glyciphage

This medicine has proven to be vital for treating type 2 diabetes. Let us take a look at the uses. 

  • Glyciphage SR 500 mg is important to control blood sugar levels and increase the body’s insulin sensitivity. 
  • Glyciphage SR 500 mg does not lower the blood sugar suddenly causing hypoglycemia. 
  • Unlike most anti-diabetic medications, it does not cause weight gain. Instead, it causes modest weight loss. Essentially, Glyciphage 500mg for weight loss is better than other anti-diabetic medications on the market.
  • Glyciphage SR 500mg uses are most important at the prediabetic stage, as it is the only medication that can help. 
  • Glyciphage SR 500 mg reduces health risks that come with high blood sugar levels like kidney damage, blindness, loss of feeling in extremities, or even amputation of the foot. These are the long-term benefits of this medication.
  • The short-term benefits are that Glyciphage SR 500 mg prevents stroke or a heart attack. 

This medicine should only be ingested when prescribed by a doctor. It should be consumed with meals to help reduce stomach or bowel-related side effects. It should be gulped down with a full glass of water. 

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How Does Glyciphage SR 500 Work?

Glyciphage SR 500mg is prescribed to people with type 2 diabetes to maintain blood glucose levels. Here is how it works.

  1. This means the body’s sensitivity to insulin needs a boost and that is what Glyciphage SR 500 mg achieves. 
  2. Glyciphage SR 500 mg reduces blood sugar production by the liver. 
  3. Glyciphage SR 500 mg delays the absorption of sugar in the bloodstream from the intestines to ensure there is no spike in glucose levels after meals. 
  4. Glyciphage 500mg uses extend beyond this as it is also prescribed to women with polycystic ovary syndrome. It regulates the menstrual cycle by lowering blood sugar levels, balancing the hormones, and assisting ovulation. 

If one has been prescribed this medicine, then the blood sugar levels need to be managed accordingly. The levels may drop suddenly when Glyciphage SR 500 mg is paired with intensive workouts, drinking alcohol heavily, or failing to eat on time. Should you change your schedule after starting with the medicine or if you notice any of these medical conditions, notify your doctor immediately. 

If you think your blood sugar level is under control, do not miss a dose of Glyciphage SR 500 mg. If you do miss a dose, consult your doctor and do not take a double dose the next time. 

Side Effects of Glyciphage SR

Although Glyciphage tablet uses can be life-saving, there are a few side effects of this medication. They are –

  1. Issues while digesting food. 
  2. Feeling of nausea which may lead to loss of appetite. 
  3. Another symptom includes vomiting. 
  4. You may suffer from diarrhea. 
  5. There may be some abdominal pain as well. 
  6. One of the uncommon yet sinister side effects is lactic acidosis. This condition is caused by too much accumulation of lactic acid in the body. The expulsion of excessive lactic acid from the blood is done by the kidney and the liver. It is essential to reveal all issues to your doctor when you go for a consultation as Glyciphage 500mg tablet should not be taken if you have kidney disease as indicated by a blood test. 
  7. Glyciphage SR 500 mg can lower the level of vitamin B12 and it is better to keep getting blood tests done from time to time. 

Your doctor may choose to ignore the Glyciphage 500 side effects if the pros outweigh the risks. 


Glyciphage SR 500 mg is an extremely beneficial medicine but it should not be consumed without a doctor’s prescription. Whenever you are going to the doctor, reveal all your issues and the extent of them supported by tests so that doctor can take an informed call. Glyciphage side effects can be misinterpreted as hypo or hyperglycemia. The dosage should be adhered to and in case of any issues or symptoms, doctors should be informed immediately. If you have made any lifestyle changes after or before starting the medicine, they should be informed to your doctor as well. 


Can this medicine be taken during pregnancy?

Is Glyciphage SR 500mg pregnancy friendly? It is not recommended during pregnancy. The doctor may prescribe if they feel that the benefits outweigh the risks. 

Can this medicine be taken while breastfeeding?

Glyciphage SR 500 mg is not recommended if you are breastfeeding or planning to breastfeed your baby. 

Does Glyciphage SR 500mg cause weight loss?

Yes, Glyciphage SR 500 mg causes weight loss in the beginning. But if you notice excessive weight loss, then inform your doctor immediately. 

Does Glyciphage SR 500mg cause sleepiness?

Sleepiness may be caused if you have a condition called lactic acidosis. This may occur due to your kidneys not functioning properly. If this happens, the doctor should be informed immediately. 

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